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Tadalafil (twenty mg) è stato studiato in associazione a 4 classi di antipertensivi. Nei soggetti che assumevano più antipertensivi, le variazioni della pressione sanguigna controllata ambulatorialmente apparivano correlabili al grado di controllo della pressione sanguigna. Nei soggetti con pressione sanguigna ben controllata, la riduzione della pressione sanguigna era minima e simile a quella osservata nei soggetti sani.
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